Cytodiagnosis of well differentiated hepatocellular carcinoma

Unusual reticulin staining pattern in well-differentiated hepatocellular carcinoma

BACKGROUND Special stains, such as reticulin stain and CD34 immunostain, are very helpful in the diagnosis of well differentiated hepatocellular carcinoma (HCC). Most studies have shown that absent or decreased reticulin stain or an abnormal reticulin pattern with widened trabeculae is reliable for the diagnosis of well-differentiated HCC. CASE REPORT We report here two cases of well differen...

Diagnosis of well-differentiated hepatocellular lesions:

The most common problems encountered in the differential diagnosis of hepatocellular lesions are: (a) adenoma vs well-differentiated hepatocellular carcinoma (HCC) in non-cirrhotic liver, (b) focal nodular hyperplasia (FNH) vs adenoma in non-cirrhotic liver, and (c) HCC vs high grade dysplastic nodules and other non-neoplastic nodules in cirrhotic liver. This discussion provides an update of im...

Workup of well-differentiated thyroid carcinoma.

BACKGROUND Well-differentiated thyroid carcinoma (WDTC) includes three main entities: papillary thyroid carcinoma (PTC), follicular thyroid carcinoma (FTC), and Hurthle cell carcinoma (HCC). A thorough knowledge of the natural history and presentation of these carcinomas is vital to the thyroid surgeon. METHODS This review details the preoperative workup of patients having or suspected to hav...

Well differentiated hepatocellular carcinoma metastasizing to jaw and oral cavity within six months of primary diagnosis.

A case of well-differentiated hepatocellular carcinoma arising in primary biliary cirrhosis.

Primary biliary cirrhosis (PBC) is a chronic progressive, autoimmune liver disease that increases the risk of hepatobiliary malignancies at a late stage. We report a 66-year-old woman with PBC combined with hepatocellular carcinoma (HCC) accompanied by hypoglycemia. Two large tumors were detected on admission and the patient died because of tumor rupture and subsequent liver failure. Histologic...